Down and out

Down but not out

By his mid-forties, Darwin had established his scientific reputation, was married with a young family and had built on the solid connections that came with his and his wife's well-known middle class families. 'He was one of the kindest and truest men that it was ever my good fortune to know,' said his influential scientific colleague, Thomas Huxley. With no need to seek employment, Darwin took ...

"Down but not out".

Out but not down

his research partner Nico Forraz. He plans to open the world's biggest institute devoted to cord blood and adult stem cells. McGuckin has been a leader of researchers working in the UK on stem cells derived from babies' umbilical cord blood. The method is less controversial than embryo-derived stem cells as no embryo is destroyed in the process. He told the Times Higher Education that France ha...

Out and down: incarceration and psychiatric disorders.

Psychiatric disorders are unusually prevalent among current and former inmates, but it is not known what this relationship reflects. A putative causal relationship is contaminated by assorted influences, including childhood disadvantage, the early onset of most disorders, and the criminalization of substance use. Using the National Comorbidity Survey Replication (N = 5692), we examine the relat...

Shut Down, Don't Stress Out

Chemical reactions lie at the heart of many biological processes, from photosynthesis and respiration to cell signaling and drug metabolism. Thanks to an atmosphere rich in oxygen, many organisms use oxygen to carry out these life processes. But oxygen metabolism produces highly toxic by-products called reactive oxygen species. When oxidation outpaces detoxifying reactions, oxidative stress occ...